Answer:
A particularly devastating conflict was the Conquest of Mexico. This conquest ocurred between 1519 and 1521, and was led by Spanish Conquistador Hernan Cortes.
Explanation:
Central Mexico was dominated by the powerful Aztec Empire. The Empire had very bad relations with its neighbors, and the Spanish used this in their favor.
The Spanish formed an alliance with the enemies of the Aztecs, and led a brutal conquests that was characterized by violence, and the spread of deadly diseases that killed most of the Aztec population.
The Spanish were victorious, and basically enslaved the surviving Native Americans, forming a Spanish colony: the colony of New Spain.
