Question

Many different types of mutations can occur within the body. Sickle cell anemia is a disease that occurs when a mutation in a base pair of the hemoglobin beta gene causes a single replacement of the amino acid glutamic acid by the amino acid valine. As a result of this mutation, the individual’s blood cells take on a sickle shape under certain conditions and form clusters that can block blood vessels and cause organ damage.

The mutation of sickle cell anemia. Red blood cells.

Which type of mutation causes sickle cell anemia?
silent
missense
insertion
frameshift

Answer 1

Answer:

Missense

Explanation:

The key in this question is  'which type of mutation causes this problem.

The description of this disease gives the the answer.  A replacement of  a glutamic acid amino acid with and Valine amino acid is called missense.

Silent mutation do not cause any difference in structure or function of the protein.

Insertions are an additional nucleotide or 2 added to the sequence

Frameshifts are the same as insertions, but the insertion occurs in part of the gene that codes for the protein.  Because of that 'insertion' the reading frame of this gene is out and the protein sequence is not correct.