Answer:
Abu Jahl and abu Lahab
Explanation:
In the pre, islamic days of ignorance theses were the most staunch enemies of Muhammad (s.a.w) and Islam before Abu Jahl use to be called Abul Hakm or Hikm meaning the father of knowledge or wise, and then nabi (PBUH )changed it to father of ignorance. As for Abu Lahab, he was the uncle of the prophet (PBUH) and he was a wretched man indeed.