Question

Which type of mutation causes this translation error that leads to cystic fibrosis? silent missense nonsense deletion

Answer 1

Answer:

The type of mutation that causes this translation error is called deletion. Deletion occurs when a section of a DNA is deleted or lost. In cystic fibrosis, three nucleotides are deleted that results in the lost of phenylalanine.

Explanation:

Answer 2

The mutation is the change in the original nucleotide sequence that can lead to cystic fibrosis. A nonsense mutation occurs in the CFTR gene that terminates the gene sequence early. Thus, option C is correct.

What is a nonsense mutation?

A nonsense mutation is a type of mutation in which the nucleotide producing the proteins are terminated early than anticipated. This cause a translational error in the case of cystic fibrosis disorder.

CFTR produces proteins that maintain the translational processes. A stop codon gets inserted in the nonsense mutation between the sequence that leads to abrupt termination of the protein sequence leading to disorder.

Therefore, the nonsense mutation causes the termination error in Cystic fibrosis.

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