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The selective permeability of a cells membrane determine what size and type of molecules can enter or not.  If a molecule has a charge and the membrane has a neutral charge the molecule has a harder time diffusing through.  The differences in charge affect permeability through a cell membrane. 
The cell has a semi-permeable membrane that allows water molecules to pass in a cell while larger molecules cannot. Lipid bilayer is an example of a biological semi-permeable membrane. The diffusion of water is called osmosis. Solutes such as salt and other contaminants are filtered.
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