The stimulation of b cells to divide and mature is provided by

B cells or B lymphocytes are produced and divided initially in the yolk sac (structure that stores the calf, a substance responsible for the nutrition of an embryo), then in the liver and later in the bone marrow, where they remain in the form of lymphoid progenitor cells until their maturation .

B cells are responsible for ensuring humoral immunity, characterized by the immune response through the production of antibodies, in order to fight invading cells such as infections by viruses or bacteria.

genewho genewho · Answer 2 · 2021-11-30T14:45:02+01:00

The stimulation of b cells to divide and mature is provided by T helper cells.

B cells participate in humoral immunity, this is characterized by the production and release of antibodies in order to destroy the antigens for which they were created.

The antigens that induce the activation of B cells can be protein, polysaccharides, lipids, etc, according to what type of antigen they require the participation of T helper cells.

T helper cells have receptors for MHCII in their membrane and binding for costimulators, which when they interact with these, activate T helper cells.

Once activated, these secrete cytokines to stimulate the proliferation and differentiation of B cells.

Cytokines are not specific for each antigen, although they have been secreted by the activation of a specific T helper cell.

Cytokines stimulate the proliferation and differentiation of B cells and they determine what type of immunoglobulin genes will be produced by the activation of B cells.

Therefore, we can conclude that the stimulation of b cells to divide and mature is provided by T helper cells.

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