(a) Based on the given data for the groups of cells cultured with 0.1% serum (groups 3 to 7), identify which of the four proteins tested do (does) not appear to play a role in blocking cell cycle entry by fibroblasts.

In this experiment, four proteins were blocked and the level of DNA replication was tested in different cell cultures to see which proteins may play a role in cell cycle. Based on the given data we can conclude that p16 is the only protein that appear to have a pivotal role in cell cycle, while p18, p21 and p27 apparently does not. We can conclude this by observing group 7 of cells, were cells have only p16 active and were able to have around 80% of DNA replication.

batolisis batolisis · Answer 2 · 2021-10-11T23:25:50+02:00

The proteins tested that do not appear to play a role in blocking cell cycle entry by fibroblasts are ; P18, P21, and P27

Based on the data provided It can seen/observed that protein P16 has a pivotal role in the cell cycle, while other proteins ( P18, P21 and P27 ) do not hold any pivotal role.

The pivotal role of P16 is evident by observing group 7 of the cells, because the cells in group 7 contain only P16 active and they also posses around 80% of DNA replication.

Hence we can conclude that the proteins tested that do not appear to play a role in blocking cell cycle entry by fibroblasts are ; P18 , P21 and P27

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