Question

A proposed mechanism for how Mediator regulates the amplitude (strength) of transcription is based on different conformational states. These, in turn, provide different degrees of efficiency for the re-entry of RNA pol II into PIC during re-initiation. According to this hypothetical model, what is postulated to determine the conformational shape of the Mediator?

Answer 1

Answer:

In thos case, different conformational states may trigger the activation of the protein function. Generally, these conformational states are the result of posttranslational modifications such as, for example, protein phosphorylation  

Explanation:

In eukaryotes, the mediator complex acts to regulate the transcriptional activity. This complex interacts with the RNA polymerase II and  transcriptional factors in order to activate transcription