Answer:
Troponin
Explanation:
This is a complex of three proteins (Trop C, I, T) that are responsible for muscle contraction of the skeletal and cardiac muscles . its binds with protein tropomysin to lie in the grove between the actin filaments. its prevents contraction by blocking myosin crossbridge in a relax muscles.Inorder to aid contractions calcium ions binds with troponin, which leads to confrontational change.This exposes myosin on actin filaments, leading to formation of crossbridge and therefore contraction of muscles.
Therefore if there is a mutation in the gene that encoded Troponin, as explained above, calcium ion will not be able to bind with tropinin, and there will be no exposure of myosin on actin filaments, no binding of myosin on actin to cause crossbridge, and consequently no muscle contraction,
Thus the intercoastal muscle and diaphragm will not contract leading to death of the baby.
Answer:
The question is incomplete, it lacks options. The options are:
A) Actin
B) Myosin
C) Acetylcholine
D) Tropomyosin
E) Troponin
The correct answer is (E)Troponin
Explanation:
Actin and myosin are proteinous filaments responsible for the force that drives the muscular system. These two proteins need to interact in order to generate this force. Here comes the role of a third protein called TROPONIN.
Troponin is a protein that plays a vital role in muscular contraction. It is a complex made up of Troponin I, C and T which binds to calcium ions that triggers a change, bringing about contraction in muscles.
What really occurs when calcium ions from the sarcoplasmic reticulum bind to the troponin complex is that the complex of troponin changes its conformation, causing tropomysin (a protein that regulates the binding of myosin to actin by covering the binding site in a relaxed muscle state) to shift from the binding sites of myosin located on ACTIN. This allows myosin to bind to actin forming a cross-bridge. This triggers muscle contraction necessary for breathing.
However, if troponin is defective due to a change (mutation) that has occurred in the gene that encodes it, the process of bringing about contraction will not be possible, which will lead to inability to breathe and subsequently death. This is the case of the new born baby.
