All proteins are synthesized by ribosomes in the cell. Some ribosomes float freely in the cytosol, while others are bound to the surface of the endoplasmic reticulum. Most proteins made by free ribosomes function in the cytosol. Proteins made by bound ribosomes either function within the endomembrane system or pass through it and are secreted from the cell. Which of the following proteins are synthesized by bound ribosomes?
Select all that apply.1. actin2. ER protein3. ribosomal protein4. insulin5. DNA polymerase6. lysosomal enzyme

2. Proteins that function within the endomembrane system (such as lysosomal enzymes and many others) or those that are destined for secretion from the cell (such as insulin) are synthesized by bound ribosomes.

3. The first amino acids in the growing polypeptide chain at N terminal act as a signal sequence. That signal sequence ensures that the ribosome binds to the outer membrane of the ER and that the protein enters the ER lumen and reaches at the final destination.

batolisis batolisis · Answer 2 · 2021-09-14T18:29:33+02:00

From the options The proteins that are synthesized by bound ribosomes are :

ER protein ( 2 )
Insulin ( 4 )
lysosomal enzyme ( 6 )

Lysosomal enzymes breakdown macromolecules taken up by organisms during the process of endocytosis, it is also membrane bound and it is synthesized by bound ribosomes.

Insulin helps in the regulation of the blood sugar levels by allowing the appropriate percentage of glucose in the blood to enter the body cells which provides the body with the necessary energy.

ER ( endoplasmic reticulum protein ) is responsible for the production of protein required by the body cells to function properly.

Hence we can conclude that the proteins synthesized by bound ribosomes are : lysosomal enzyme, Insulin and ER protein.

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