Cell culture inserts/microporous membranes promote the proper phenotype of a variety of endothelial cells including kidney cells, intestinal epithelial cells and others. Equally as important is the fact that these devices can be used to study transcytosis, a process discussed briefly in the cell culture lecture.

What is transcytosis and why does the device described above allow one to study this process compared to a typical, plastic cell culture plate?

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Answer:

Explanation:

Transcytosis is the transfer of molecules across cells from one side to the other, a process that entails endocytosis, vesicular transfer and exocytosis, and which speeds the bulk movement of molecules through tissues.

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