After the bases of DNA were identified, Erwin Chargaff analyzed the percentages of adenine, thymine, guanine, and cytosine in the DNA of many different organisms. This table shows the percentages of A, T, G, and C for a human, a bacterium, and a fish. Chargaff observed an approximate rule about these percentages in all of his samples: What is the rule?

A.
A + T = G + C

B.
A = G; T = C

C.
A = C; T = G

D.
A = T; G = C

Chargaff's rules state that "DNA from any cell of any organisms should have a 1:1 ratio (base Pair Rule) of pyrimidine and purine bases and, more specifically, that the amount of guanine should be equal to cytosine and the amount of adenine should be equal to thymine".

This pattern is noticed in the DNA strands.

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kasliwalalvi24 kasliwalalvi24 · Answer 2 · 2022-01-11T09:54:16+01:00

DNA is a nucleotide made up of pentose sugar-phosphate backbone, and nitrogenous bases. The ratio of nitrogenous bases in the DNA was suggested by Erwin Chargaff.

The rule of Chargaff is correctly described by the A = T; C = G.

What is Chargaff's Rule?

Chargaff's rule states that the DNA of any species of any organism will have the stoichiometric ratio of purines and pyrimidines.

Specifically, the amount of guanine will be equal to cytosine, and the amount of adenine will be equal to thymine.

Thus, the correct answer is Option D.

Learn more about Chargaff's rule here:

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