Answer: C.) male 5 and female 6
Explanation: A pedigree chart represents the inheritance of a specific trait or traits along generations. In the representation, squares are male and circles are female.
The question asks for least likely to have offspring with the disorder. Analysing the chart, it is observed that male 1 and female 2 have offsprings with shaded shapes: individuals 3, 7 and 10, so their probability of having children with the disorder is not small. It's 3 in 5.
Male 3 and female 4 also have an offspring with a genetic disease, so ti's not this couple.
Male 9 and female 10 have 2 offspring with the disorder. So their probability is not so low.
Male 5 and female 6 are the only couple without an offspring with the trait. So, their chance of having an offspring having the disorder is the least.
In conclusion, couple 5 and 6 have the least probability of having an offspring with the genetic disorder.
