Answer:
In prokaryotes nucleus is not present so replication transcription and translation takes place in the cytoplasm in the prokaryotes while in eukaryotes replication and translation takes place in the nucleus.
In prokaryotes, transcription and translation are coupled but in eukaryotes, transcription and translation are separated by nucleus and post-transcriptional modification takes place in eukaryotes, not in prokaryotes.
In prokaryotes, ATP synthesis takes place in cell membranes because they do not have mitochondria. Eukaryotes contain mitochondria where ATP synthesis takes place in them.
