Identify the correct sequence of steps in the generation of an action potential. 1. Activation of sodium channels and rapid depolarization 2. Inactivation of sodium channels and activation of potassium channels 3. Depolarization to threshold 4. Closing of potassium channels

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Answer:

The sequence is: 3,1,2,4

Explanation:

It is understood as the potential of action to the electric wave that originates from the changes that the neuronal membrane undergoes due to the electrical variations and its relation between the external and internal means of the neuron. It begins in the axon cone, where a large number of sodium channels are observed. Its phases are as follows:

-resting potential

-depolarization

-repolarization

-hyperpolarization

-resting potential

-the potential for action and release of neurotransmitters

The correct steps in the generation of an action potential is 3, 1, 2, 4.

• A brief reversal of membrane potential where the membrane potential varies from -70 millivolts to +30 millivolts is termed as the action potential.  

• The action potential possess three main phases, that is, depolarization, repolarization, and hyperpolarization.  

• When the positively charged sodium ions moves into a neuron with the opening of voltage-gated sodium channels it is known as depolarization.  

• The closing of the sodium ion channels and the opening of the potassium ion channels results in repolarization.  

• Due to an excess of open potassium channels and the efflux of potassium from the cell hyperpolarization takes place.  

• The depolarization is also known as the rising phase, which results when the positively charged sodium ions suddenly rush in via the open voltage-gated sodium channels.  

• The repolarization also known as the falling phase due to slow closing of the sodium channels and the opening of the potassium channels.  

• Hyperpolarization is a phase of increased permeability of potassium resulting in excessive potassium efflux before the closing of the potassium channels.  

Thus, the correct sequence of the generation of an action potential is 3, 1, 2, 4.

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