Question

During infection, C. diphtheriae expresses a variety of genes that are used to establish infection and cause disease. One of these genes encodes for diphtheria toxin. Expression of the toxin requires the genetic information contained in DNA be converted into protein. The 1st step in this process is transcription, in which DNA is converted into MRNA The following is a short piece of the DNA sequence for diphtheria toxin (written 5' to 3) TAA GCG TAG AAC TTG. Which of the following sequences represents the mRNA (written 5' to 3) that will be generated from this template DNA sequence? A. CAA GUU CUA CGC UUA B. AUU CGC AUC UUG AAC C. CAA GTT CTA CGC TTA D. ATT CGC ATC TTG AAC

Answer 1

Answer:

B. AUU CGC AUC UUG AAC

Explanation:

According to the rule of base pairing in DNA, the pyrimidine bases always pair with purine bases. Specifically, adenine (A) always pair with thymine (T) while Guanine (G) always pair with cytosine (C). In RNA, thymine is replaced by uracil (U).

Hence, TAA GCG TAG AAC TTG  will give

             AUU CGC AUC UUG AAC.

The correct option is B.