The statement that describes a major difference between Roman Catholicism and Protestantism is that Catholicism requires Christians to follow a single leader, while Protestantism does not require to do so. Therefore, the option C holds true.
What is the significance of difference between Roman Catholicism and Protestantism?
Under Roman Catholicism, extensive amount of architectural designs are given to the churches, whereas the protestant churches are often plain and simple. Where majority of Catholics follow Latin verses, protestants give more focus upon their vernacular language.
The biggest difference, however, between Catholicism and Protestantism is that those who follow Catholicism believes in a single supreme leader, whereas, those who follow Protestantism do not any such beliefs.
Therefore, the option C holds true regarding the significance of the difference between Roman Catholicism and Protestantism.
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