Question

The typical dosage of statin drugs for the treatment of high cholesterol is 10 mg.Assuming a total blood volume of 5.0 L and the density of blood in healthy individuals is approximately 1.05 g/mL, report the concentration of drug in units of ppm.

Answer 1

Answer:

1.904 ppm

Explanation:

Concentration of drug in units of ppm = mass of solute ÷ (mass of solution ) × 1000000

mass of blood = density of blood × volume = 1.05 g / ml × 5000 ml = 5250  g

mass of solution = mass of blood + mass of solute ( statin) = 5250 + 0.01 g  = 5250.01 g

Concentration of drug in units of ppm = (0.01 g / 5250.01 g) × 1000000 = 1.904 ppm