Question

During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD+ if glycolysis is to continue. The most important reaction involved in the reoxidation of NADH is:

A) dihydroxyacetone phosphate → glycerol 3-phosphate
B) glucose 6-phosphate → fructose 6-phosphate
C) isocitrate → α-ketoglutarate
D) oxaloacetate → malate
E) pyruvate → lactate

Answer 1

Answer:

The answer is pyruvate → lactate

Explanation:

In the reaction of glycolysis, glucose breaks down to form pyruvate yielding ATP and NADH.

Under or during strenuous exercise, which is an anaerobic condition, lactate is formed by the reoxidization of NADH and the conversion of pyruvate to lactate.