Answer:
The protein will dysfunction which will lead to osmotic gradient imbalance in the cell.
Explanation:
In facilitate, diffusion proteins are required to allow the movement of molecules in and out of the cell along their concentration gradient. The protein changes its conformation to transport the molecules across the plasma membrane.
So if a toxin prevents conformation change in membrane protein then the facilitated diffusion of molecules by that protein will stop which will increase the gradient of that molecule outside the cell membrane. Therefore it will lead to an osmotic imbalance of molecules in the cell.