Question

5. The nurse is providing dietary instructions to a cli-
ent who has been prescribed cyclosporine. Which
food item should the nurse instruct the client to
exclude from the diet?
1. Red meats
2. Orange juice
3. Grapefruit juice
4. Green, leafy vegetables

Answer 1

Answer:

3. Grapefruit juice

Explanation:

Rationale: a compound present in grapefuit juice inhibits metabolism of cyclosporine through the cytochrome P450 system. As a result, consumption of grapefruit juice can raise cyclosporine levels by 50-100%, thereby greatly increasing the risk of toxicity. Red meats, orange juice, and green leafy vegetables do not interact with the cytochrome P450 system

Answer 2

Grapefruit juice is the answer to this question