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Answer:

Drug calculation

If we have 45g of clobetasol  = 0.05%w/w

Then what mass in g of clobetasol is in 0.03%w/w = 45 x 0.03/0.05 =27g

It means that 27g of clobetasol must be added to change the drug strength to 0.03% w/w

30 g of ointment base needed to 45 g of clobestasol (TEMOVATE) ointment of 0.05% w/w to change its strength to 0.03% w/w

Let x represent the amount of ointment base needed to 45 g of clobestasol (TEMOVATE) ointment of 0.05% w/w to change its strength to 0.03% w/w

Therefore:

45g * 0.05% = (x + 45) * 0.03%

45 * 0.05 = (x + 45) * 0.03

0.03x + 1.35 = 2.25

0.03x = 0.9

x = 30 g

30 g of ointment base needed to 45 g of clobestasol (TEMOVATE) ointment of 0.05% w/w to change its strength to 0.03% w/w

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