Question

The pediatric oral dose of ciprofloxacin is given as 10 to 20 mg/kg every 8 hours, not to exceed a single dose of 400 mg irrespective of body weight. If a child weighing 55 lb. is prescribed a one-teaspoonful dose of 5% ciprofloxacin oral suspension every 8 hours, calculate whether or not the dose prescribed is within the therapeutic range. Your answer should be "Yes" or "No".

Answer 1

Answer:

No. 5% of ciprofloxacin oral suspension for this child exceeds the therapeutic range.

Explanation:

Single dose of ciprofloxacin suspension shall be 400 mg

the pediatric oral dose is 10-20 mg/kg and body weight of child is 55 lb.

1 kg is 2.2 lb= 55÷ 2.2 = 25 kg

minimum required dose for child is 25 × 10= 250 mg

maximum required dose for child is 25 × 20 = 500 mg

1 teaspoonful is 5000 mg.

500 mg ÷ 5000 mg = 0.1 tsp

Hence, the dose exceeds the therapeutic range.

Answer 2

Based on the information given, the does that is prescribed isn't within the therapeutic range. Therefore, it's false.

From the information given, it should be noted that the following can be depicted:

• Single dose of ciprofloxacin suspension = 400 mg.
• Pediatric oral dose = 10-20 mg/kg
• Body weight of child = 55 lb.

• 1 teaspoonful = 5000 mg.

Since 1 kg is 2.2 lb, therefore, 55lb will be 55 / 2.2 = 25 kg

Therefore, the minimum required dose for the child will be given as:

= 25 × 10= 250 mg

The maximum required dose for the child is given as:

= 25 × 20 = 500 mg

Therefore, the dose will be:

= 500 mg / 5000 mg

= 0.1 teaspoon.

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