Aniridia is a human condition in which the eye has no iris. The protein encoded by the gene responsible for Aniridia is very nearly identical to the protein product of the fly eyeless protein. What experiment could provide evidence that the two genes are functionally equivalent? A. Introduce the aniridia mutation into Drosophila embryos to look for iris formation. B. Sequence the eyeless and aniridia DNA sequence and regulators. C. Use the Eyeless mRNA as a probe in other invertebrate and non-mammalian species. D. Introduce the mouse aniridia wild-type sequence into the fly to see whether flys eyes develop. E. Introduce the mouse wild-type sequence into the fly egg to see whether mouse eyes develop.

Respuesta :

Answer:

Option B. Sequence the aniridia and eyeless DNA sequence and regulators.

Explanation:

DNA sequencing:

It is the method of determining the sequence of nucleic acid. DNA sequence includes the method to determine the order of nucleotide sequences. Through the process of sequencing aniridia and eyeless DNA are sequenced and analysed on Gel electrophoresis. Sequencing similarity shows evidence that the two genes are functionally equivalent.

Best choice:

B. Sequence the eyeless and aniridia DNA sequence and regulators.

The experiment could provide evidence that the two genes are functionally equivalent - D. Introduce the mouse aniridia wild-type sequence into the fly to see whether fly's eyes develop.

Aniridia

is a human condition in which the eye has no iris.

  • The protein is encoded by the PAX6 gene.
  • this gene is responsible for Aniridia by mutation is very nearly identical to the protein product of the fly eyeless protein.
  • if we introduce the mouse aniridia wild-type sequence or gene into a fly and check the result we would be able to find evidence that the two genes are functionally evident
  • if fly develops eyes then both are functionally equivalent.

Thus, The experiment could provide evidence that the two genes are functionally equivalent - D. Introduce the mouse aniridia wild-type sequence into the fly to see whether fly's eyes develop.

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