Answer:
a. they are designed to be resistant to certain antibiotics
Explanation:
Most of the Bacteria that contain recombinant plasmids as antibiotic-resistant gene. This antibiotic-resistant gene can be used as a selectable marker.
To isolate these bacteria, you will have to inoculate and grow them in a medium containing the antibiotic. Take for example, a recombinant plasmid which has an ampicillin-resistant gene is grown in an ampicillin antibiotic medium since other bacterias present won't be able to grow in the medium due to the lack of the ampicillin-resistant gene.