Multiple couples living in a small village in the eastern African lowlands, all of whom are heterozygous for the HbS allele, have 500 children among them. Of these children, 139 are homozygous for HbA, 279 are heterozygous for HbS, and 82 suffer from sickle cell disease. Are these data statistically significant? Explain using a chi-square statistical analysis test.
