Answer:
D) lining up of chromosomes in the cell
Explanation:
Prophase can be described as the first stage of cell division. During this phase, The chromatin material condenses and becomes compact so that the chromosomes become visible. The nuclear envelope disintegrates and the nucleolus disappears. Hence, the choices mentioned in option A, B and C occur by the end of prophase.
Metaphase is the third phase of cell division. During this phase, the chromosomes line themselves in the centre of the cell. Hence, the lining of the chromosome does not occur by the end of prophase. This occurs during the third stage.
