Respuesta :
Answer:
0.25%
Explanation:
20 people start the new population. So there are 20 genes or 40 alleles for the recessive disorder phenylketonuria. 2 out of 40 alleles are recessive for the condition hence frequency of the allele = 2/40 = 0.05
Frequency of the allele does not change when the population increases so it is in Hardy-Weinberg equilibrium. According to it, if q is the frequency of recessive allele, q² = frequency of the recessive condition
Here, q = 0.05 So,
q² = (0.05)² = 0.0025
In percentage, it is 100 * 0.0025 = 0.25%
Hence, incidence of phenylketonuria in the new population is 0.25%
Hence, 0.25% of the population will be born with Phenylketonuria.
Hardy-Weinberg principle:
The principle states that the allelic frequency remains constant through generations and the gene pool remains constant. This phenomenon is called genetic equilibrium.
The population of 20 people comprises 40 alleles. Out of these 40 alleles, 2 are for phenylketonuria.
Assigning this allele to [tex]q[/tex],
We get,
[tex]q=\frac{2}{40}\\ q=5\%[/tex]
Now as per the Hardy-Weinberg principle, if the frequency of the recessive allele in a population is [tex]q[/tex] then the incidence/frequency of recessive allele individuals will be,
[tex]q^2=q\times q\\=0.05\times 0.05\\q^2=0.0025\\=0.25\%[/tex]
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