Question

A drug that prevents assembly of the mitotic spindle would cause the cell cycle to stall just after
A. chromosome condensation
B. attachment of the spindle to the chromosomes
C. all the chromosomes have lined up in the middle of the cell
D. the separation of sister chromatids
E. cytokinesis

Answer 1

Answer:

The correct answer will be option-A

Explanation:

Colchicine is the drug that prevents the assembly of the mitotic spindles which halts or stops the cell cycle.

The colchicine acts by inhibiting the microtubule polymerization thus mitotic spindles which takes place after the condensation of the chromosomes during prophase and pre-metaphase.

This acts as checkpoint which can halt the cell cycle at the phase of chromosome condensation.

Thus, option-A is the correct answer.