Question

Put the events associated with the mechanism of action of cholera in the correct sequential order.
1. Adenylyl cyclase is turned on, producing cAMP.
2. Cholera binds to intestinal cells.
3. CFTR channels are opened, increasing Cl-diffusion into the lumen of the intestine.
4. Cholera is brought into the cell via endocytosis.

Answer 1

Answer:

2,4,1 and 3.

Explanation:

Cholera toxin is an epidemic disease caused by the bacteria. This mainly causes watery diarrhea and results in the extreme loss of fluid from the body and causes electrolyte deficiency in the body.

The cholera is a toxin is produced by the bacteria. This toxin has the ability to enter in the intestinal cells. This enters into the cell by the endocytic process. This toxin causes he activation of cAMP in the body. cAMP activates the protein kinase A, this causes the opening of CFTR channel. This channel opens the chloride diffusion and results in the loss of chlorine ions from the body.

Thus, the correct order is 2,4,1 and 3.