A match between the DNA in a sample and the genomic DNA of a particular individual for a single tandem repeat site is not sufficient to establish identity. However, a mismatch is definitive. The primary reason is that:

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Answer:

The mismatch is definitive, the primary reason is that, the DNA in the sample must match the original genomic DNA.

Explanation:

  • Tandem repeat takes place only when 'one or more nucleotide pattern is repeated' and it is 'adjacent' to each other.
  • Mismatch indicates that the sample DNA is not the source for that Original DNA.
  • If the sample is the actual source of the original genomic DNA, then it must be matched exactly.

The DNA is matched with the sample DNA in the process of DNA fingerprinting. The mismatch of DNA is representative that the DNA sample does not belong to the original DNA.

What is DNA fingerprinting?

DNA fingerprinting is the process of matching the DNA sample with the original DNA based on the tandem repeats.

The tandem repeat is the repeated unit of the nucleotides in the genetic material. When the sample DNA did not match the original DNA strands, it is the representation of mismatch.

The mismatch in the DNA sequence describes the absence of relation between the original and sample DNA.

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