Question

Researchers studying yeast discovered that, for some mutants, when the temperature at which the cells are grown is elevated from 25ºC to 37ºC, their secretory pathway no longer functions and the cells grow dense with unsecreted protein. When these cells are examined microscopically, they can be divided into groups that vary in terms of where the unsecreted proteins accumulate. In some of the mutants, proteins accumulate in the ER; in others, the Golgi; in others, they accumulate in vesicles near the plasma membrane. What is the likely explanation for this difference in appearance?

Answer 1

Answer:

The correct option is ' Different temperature-sensitive mutations affect different stages of the transport process.'

Explanation:

Specific genes make mRNA for a protein by the process of transcription. Protein is made from the mRNA by the process of translation in the ribosomes.

After the synthesis of a protein, it travels to the Endoplasmic Reticulum where it is packaged, then to the Golgi complex where they are modified and packaged. From the Golgi complex, they move out of the cell to where they have to function through vesicles. Hence, the mutation due to which the proteins accumulate in ER, Golgi and vesicles show that the mutations have affected the transport process.