The DNA in a cell's nucleus encodes proteins that are eventually targeted to every membrane and compartment in the cell, as well as proteins that are targeted for secretion from the cell.For example, consider these two proteins:1. Phosphofructokinase (PFK) is an enzyme that functions in the cytoplasm duringglycolysis.2. Insulin, a protein that regulates blood sugar levels, is secreted from specializedpancreatic cells.Assume that you can track the cellular locations of these two proteins from the time that translation is complete until the proteins reach their final destinations.For each protein, identify its targeting pathway: the sequence of cellular locations in which the protein is found from when translation is complete until it reaches its final (functional) destination. (Note that if an organelle is listed in a pathway, the location implied is inside the organelle, not in the membrane that surrounds the organelle.)Options:a. Cytoplasm only, ER --> cytoplasm, b. ER --> Golgi --> outside cell, c. cytoplasm --> ER --> outside cell, d. Golgi --> ER --> outside cell, e. cytoplasm --> Golgi --> outside cell, f. nucleus --> cytoplasm, g. ER --> Golgi --> cytoplasmProtein Targeting PathwayPFK _Insulin _

As the enzyme PFK functions in the cytoplasm hence, it won't have to undergo the process of modification after its production. It will be directly present in the cytoplasm of the cell.

As for insulin, after the protein is made by the ribosomes by translation, the protein will enter the endoplasmic reticulum where it will be folded and vesicles will form around it. From the ER, the protein will travel to the Golgi complex where it will be modified and packed. From the Golgi complex, the protein will move outside the cell to areas where it has to function.