Answer:
The correct answer is d The enzyme has an allosteric regulatory site.
Explanation:
The allosteric site of an enzyme does not contribute to substrate specificity of an enzyme because allosteric site does not act to bind with the substrate because allosteric site is a regulatory site of an enzyme which interacts with modulators molecules.
All the other options mentioned in the question contribute to substrate specificity of an enzyme such as similar shape exist between a pocket on the surface of the enzyme and functional group on the substrate. The enzyme undergo Configurational change in response to substrate binding.