Answer:
C. Endocrine
Explanation:
In endocrine signalling cells send signals or hormones over long distances. Hence the hormone can be produced at one part of the body and the effect can be observed at entirely different part of the body.
Addison's disease is an endocrine disorder characterised by fatigue, muscle weakness, darkening of skin etc. In the disease, adrenal glands do not produce sufficient amount of hormones cortisol and aldosterone. Cortisol is a glucocorticoid whereas aldosterone is a mineralocorticoid. Together these hormones travel in the body and affect many body functions like