Answer:
Replication proceeds in both directions from a single origin of replication.
Explanation:
The origin of replication is the DNA sequence where the process of DNA replication begins. Prokaryotes such as E. coli, mostly have smaller genome sizes as compared to the eukaryotes and have a single origin of replication. The DNA helicases serve to unwind the DNA at the origin of replication and create replication forks.
The origin of replication is an AT-rich sequence where DNA is easily denatured to produce single strand bubbles or the replication loops. Both the separated DNA strands are replicated simultaneously. The replication is bidirectional which means that both ends of the separated DNA loop have active replication forks. The process of DNA replication continues until both the replication forks meet to replicate the complete DNA.