Answer: A- Down on his luck
Explanation: In the first lines, we get to see the persona's negative feelings towards life. For example in lines 1 and 2 'When in disgrace with Fortune and men's eyes, I all alone beweep my outcast state'. In these lines the persona says he is all alone and sad which shows how down on his luck he is. Another instance showing how bad he is doing is in line 4: 'And look upon myself and curse my fate'. Here the persona tells us he curses his fate thus once again showing us he is not all right