Answer:
The correct option is: an increase in body temperature due to high fever
Explanation:
Denaturation of protein is a process by which the protein unfolds i.e. loses it's quaternary, tertiary, and the secondary structure when exposed to high temperature (above 41°C), change in pH or chemical denaturants. Denaturation of proteins leads to loss of activity.
The enzymes pancreatic proteases breaks down proteins by hydrolysis, thus leading to the denaturation of protein.
Since, generally fever does not increase the body temperature above 41°C. Therefore, it doesn't lead to denaturation of protein.