Question

Hemophilia is an X-linked trait caused by the allele h. About 1 in 10,000 males (0.0001) has hemophilia. The frequency of the h allele in males is therefore _____________________.

Answer 1

Answer:

The frequency of the h allele in males is $0.01$

Explanation:

Given ,

Out of 10,000 males , only one male has hemophilia.

This means that the probability of occurrence of hemophilia is

$\frac{1}{10000} \\= 0.0001$

This also signifies that the probability of occurrence of genotype causing hemophilia is $0.00001$

As per Hardy Weinberg's equation,

probability of occurrence of a dominant genotype is represented by $p^{2}$

Here $p^{2} = 0.0001$

Frequency of allele h will be given by

$\sqrt{p^2}$

$\sqrt{0.0001} \\= 0.01$