Answer: Enzyme compartment cannot be used as metabolic control mechanism.
Explanation: Metabolic control or regulation employs many substrates,enzymes and byproduct to send a signal to cells to perfom or stop perfoming certain duties. Too much glucose for instance will regulate, activate and send signals using insulin to store glucose in form of glycogen using the process of glycogenolysis. Hormones and enzymes will also signal to activate the process of sleep, menstruation, digestion etc activating and regulating different kind of cells.
On the other hand enzyme cormpartmentation is there to maintain order and protect cells from lysis by making sure that each enzyme and cell works in its own confined space.