Answer:
Most of free energy available from oxidation of the glucose remains in pyruvate.
Explanation:
The overall reaction of the process glycolysis is:
Glucose + 2 NAD⁺ + 2 ADP + 2 Pi ⇒ 2 Pyruvate + 2 NADH + 2 H⁺ + 2ATP
Glucose is oxidized to give 2 molecules of pyruvate and 2 molecules of NADH and ATP (Energy currency).
Though the free energy of oxidation of glucose is high but only 2 NADH is formed because the most of the free energy that is being released from the oxidation of glucose remains in the pyruvate which is produced in the reaction and thus only 2 molecules are formed.
The formation of only two molecules of NADH during glycolysis is because
Glycolysis is the cytoplasmic pathway through which glucose is oxidized into 2 three carbon compounds + energy.
The overall reaction process of glycolysis is ;
Glucose + 2 NAD⁺ + 2 ADP + 2 Pi ⇒ 2 Pyruvate + 2 NADH + 2 H⁺ + 2ATP
From the reaction process of glycolysis shown above,the oxidation of Glucose produces 2 NADH and 2 molecules of ATP . most of the energy remains in the 2 molecules of Pyruvate and that is why only two molecules of NADH is formed during the overall process of glycolysis
Hence we can conclude that The formation of only two molecules of NADH during glycolysis is because Most of the free energy produced during glucose oxidation stays in Pyruvate.
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