Answer: In global alignment an end to end alignment is made in the entire sequence however in local alignment a local region is found wit the highest level of similarity in their sequences.
Explanation:
Global alignment is more suitable for closely related sequences whereas local is suitable for divergent sequences.
global alignment is used for comparing genes base on same functionalities whereas local alignment is used to find sequences in DNA.
EMBOSS needle is a global alignment tool and BLAST is a local alignment tool
