1. The impact that the Europeans had o the New World in their early explorations was mostly negative. The Europeans were treating the natives very badly. Several diseases quickly spread around a big portion of the native populations died out. The greed from the Europeans for wealth, especially gold and silver, led to wars and battles with the natives, with he end result being the destruction of the most developed civilizations of the Americas.
2. The impact of the New World on the Europeans was mostly good, with slight negativity. The negative part was the spreading out of few diseases which affected solid number of Europeans and turned out to be fatal for them, but on a large scale. The positives were seen in the large amounts of gold and silver, later platinum as well, that were obtained by the Europeans from the New World. Also, lot of new crops were introduced in Europe, some of which, like the potato, had a huge positive impact and mostly solved the malnutrition problem which was common prior to its introduction.