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DNA ligase is a DNA- joining enzyme. if two pieces of DNA Has matching ends, ligase can link them to form from a single, unbroken molecule of DNA. in DNA cloning, restriction enzymes and DNA ligase are used to insert genes and other pieces of DNA plasmids.

DNA Ligase joins two pieces of DNA together

What is DNA ligase ?

  • DNA ligase is a DNA-joining enzyme.

  • If two pieces of DNA have matching ends, ligase can link them to form a single, unbroken molecule of DNA.

  • As synthesis proceeds, an enzyme removes the RNA primer, which is then replaced with DNA nucleotides, and the gaps between fragments are sealed by an enzyme called DNA ligase.

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