Isolate the plasmids of the bacterium, and use the same restriction endonuclease you have used to cut the gene for blood clotting proteins, to cut open the plasmid. Then use a ligase enzyme to join the genes with the open plasmid, to create a reccombinant plasmid. The plasmids are then taken up by the bacterium. The bacteria can multiply in a culture containing nutrients, so more genetically modified bacteria with the blood clotting genes, are produced. Or the bacteria can grow in a fermenter to produce commercial quantities of the protein
