Take this step by step first look at the top 5-2(6-2*3) try to simply the parenthesis first just like PEMDAS
6-2*3 first multiply 2*3 =6 then 6-6 is 0 so that does not get rid of it still because now we have 5-2(0) you multiply the 2*0= 0 so now you just have five on the top
Now we are done with the top move to the bottom
The Denominator (bottom of fraction) is 5(2+2*4) again PEMDAS and do parenthesis first (2+2*4)= (2+8)= 10
Now it was in parentheses so you have to multiply -5(10) =-50
Last now that you have simplified the numerator and denominator you put them together 5/-50 = 1/-10