New mutations can also occur randomly, so there’s a chance that children of parents who didn’t inherit the gene for Huntington’s can develop a mutation in the gene that causes Huntington’s disease.
Huntington’s is a brain disease caused by autosomal dominant gene inheritance. The disease might be caused in the progeny due to the mutation even when the parents are normal.
An autosomal dominant disorder is caused when the disease-causing genes are located on the dominant allele of the autosomal or the somatic cells. The disease can be caused in the offspring even when they are in the heterozygous condition.
Huntington’s disease is an example of an autosomal dominant disease that gets inherited from the parent to the offsprings and are passed when they are present even on one gene of the parent allele.
There is a chance that the disease might be present in the child even when the parents are normal for disease. This case might be due to mutation that can cause changes in the genes of the offspring resulting in the disease.
Therefore, the disease can be caused in the offspring due to mutation.
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