In the eukaryotes, the activator proteins binds to the DNA enhancers. There they attract the proteins, which then activate the RNA (Ribonucleic Acid) polymerase, and ultimately the process of transcription. The generalized transcription factors, on the other hands, binds to the promoter regions of the DNA (Deoxyribonucleic acid). The attachment of the RNA polymerase enzyme to the promoter region of the DNA is necessary for transcription. The generalized transcription factors helps the RNA polymerase enzyme to attach to the promoter region.