Please help me with this one

So, the denominators are the same again. This means you should just work on the numerators. Combine them first to get:
s - 6 - (-4s - 4)
We distribute the negative 1 to get:
s - 6 + 4s + 4
We combine like terms:
5s - 2
And, that's your numerator. You put that on the denominator to get: (5s - 2)/(s + 4)