The proofreading mechanism that occurs during DNA replication is conducted through polymerase. ____ activity in ____ a. S' to 3 ' exonuclease; RNA b. 3' to 5 ' exonuclease; DNA c. 3' to S' exonuclease; RNA d. 2' to 3' exonuclease; DNA e. 5' to 5 ' exonuclease; RNA